Comparision of intravenous magnesium sulphate and lignocaine in attenuation of pressor response to laryngoscopy and endotracheal intubation

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چکیده

Endotracheal intubation and laryngoscopy are noxious stimuli provoke cardiovascular autonomic responses because of sympathoadrenal stimulation. Attenuation significant increases in heart rate blood pressure decreases the risk complications.Various pharmacological non-pharmacological methods have been tried to attenuate hemodynamic response endotracheal intubation. None approaches proved be ideal.In view it present study was undertaken evaluate compare effects intravenous magnesium sulphate 30mg/kg lignocaine 2mg/kg attenuation pressor intubation.Prospective randomized controlled conducted which 60 American society Anesthesiologist 1 patients, aged 18-60yrs, undergoing elective surgery under general anesthesia were selected. Patients into 2 groups: Group with thirty patients who received MgSO4 mg/kg bolus. Anesthesia induced using premedication glycopyrolate, midazolam, ondansetron injection Fentanyl administered as analgesic agent. Study drug Injection mgso4 90sec before induction propofol agent followed by succinylscoline facilitate Laryngoscopy both groups studied recording Heart Rate (HR), (BP), at baseline,after administering drug, laryngoscopy, after intubation, 1min,3min,5minsafter intubation.Study revealed that had decreasing trend HR MAP recorded till 5mins Mgso4 has vasodilator properties significantly suppresses release catecholamines hence can stress better than lignocaine.

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ژورنال

عنوان ژورنال: International journal of medical anesthesiology

سال: 2022

ISSN: ['2664-3766', '2664-3774']

DOI: https://doi.org/10.33545/26643766.2022.v5.i3a.357